Literature summary extracted from
Leonidas, D.D.; Maiti, T.K.; Samanta, A.; Dasgupta, S.; Pathak, T.; Zographos, S.E.; Oikonomakos, N.G.
The binding of 3-N-piperidine-4-carboxyl-3-deoxy-ara-uridine to ribonuclease A in the crystal (2006), Bioorg. Med. Chem., 14, 6055-6064.
Crystallization (Commentary)
EC Number |
Crystallization (Comment) |
Organism |
---|
4.6.1.18 |
in complex with inhibitor 3-N-piperidine-4-carboxyl-3-deoxy-ara-uridine at 1.7 A resolution. Two inhibitor molecules bind in the central cavity of enzyme, the first occupying the purine-preferring site, and the second molecule binding to the carboxyl group at the pyrimidine recognition site |
Bos taurus |
Inhibitors
EC Number |
Inhibitors |
Comment |
Organism |
Structure |
---|
4.6.1.18 |
3-N-piperidine-4-carboxyl-3-deoxy-ara-uridine |
binding of two inhibitor molecules in the central cavity of enzyme |
Bos taurus |
|
Organism
EC Number |
Organism |
UniProt |
Comment |
Textmining |
---|
4.6.1.18 |
Bos taurus |
P61823 |
- |
- |